Author: Pooja Baviskar

Deadly toxic ricin found with Tunisian extremist, in Germany.

As reported by the prosecutors of Germany on Thursday, an Islamic extremist has been thwarted planning a mortal attack with fatal toxin ricin, which is a highly poisonous protein obtained from the pressed seeds of castor oil plant.

According to the government prosecutors, a man Tunisian aging 29 years recognized as Sief Allah H. has been arrested on Wednesday, who started acquiring materials online that included the seeds to produce ricin in May. The suspected man lived in the Chorweiler neighborhood of Cologne with his wife and four children.

The man was reportedly successful in making toxic ricin this month; fortunately the federal investigators grabbed it while searching his apartment in Cologne. However, the examiners are still in search to know how the man might have planned the use of toxin, alleging he was planning for an attack in Germany.

A terrorism expert, Elmar Thevessen said in a statement that, “Ricin is deadlier than then the venom of a cobra. A tiny amount is enough to kill an adult. In can be dissolved in water or added to food. There is no antidote.”

Investigators said that, “He procured 1,000 castor bean seeds online as well as an electronic coffee grinder.” They reported that as of now, there are no strong evidences have been yet obtained that can be connected with any extremist organization. They did not mentioned any immediate comment to the reporters as the American intelligence overturned off German investigators.

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Special counsel Mueller indicts Paul Manafort for witnesses tampering, reports a DC District Court filing on Monday. According to the filing, one of the witnesses has recently yielded during the investigation that a former Trump campaign chairman and American lobbyist, Paul Manafort asked them for mendacity about the persuading effects on which they worked for him in the United States.

Special counsel Mueller is urging to the court for a revise or rescind of the pretrial release of Paul Manafort, who was already accused of 23 counts and yet more wrongdoings like attempting to tamper witness.

However, Mueller does not strive to file a new charge on the federal lawyer, but he wants to halt Manafort’s pretrial release from the house arrest, according to the Mueller’s argument. Brock W. Domin, FBI agent informed that an associate of Manafort, who is an executive at a public relations firm – to be referred as only Person A – told the government that he recognized Manafort’s outreach of suborn perjury and forced others to lie at the federal investigations.

DC District Court filing worded that, “Manafort’s obstructive conduct ― carried out at a time when he was seeking relief from his current conditions of release ― instills little confidence that restrictions short of detention will assure Manafort’s compliance with the Court’s orders and prevent him from committing further crimes.”

FBI’s Brock W. Domin said in a statement that, “The two potential witnesses believed the messages and phone calls were “an effort to influence [their] testimony.”

 

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Now breast cancer can be diagnosed earlier without chemotherapy, before get spreading through the lymph nodes according to the recently published study. The researchers associated with the study recently analyzed that the patients having smaller tumors in size which had not spread over the lymph nodes could be treated without applying chemo treatment.

The study has been published in the New England Journal of Medicine and presented at the meeting of American Society of Clinical Oncology on Sunday. Since, the further studies are yet to go through the examinations of those women participants on whom the research findings are based.

However, the researchers and health experts are urging to be cautious about the applications and effectiveness of the treatment, the findings suggest it should not be applied to the patients with larger sized tumors or a cancer stage that has begun spreading or metastasizing.

Study’s author, Dr. Ingrid A. Mayer from the Vanderbilt University Medical Center said in a statement that, “We can spare thousands and thousands of women from getting toxic treatment that really wouldn’t benefit them. This is very powerful. It really changes the standard of care.”

Associate professor and breast medical oncology director, Dr. Sara Hurvitz from the Jonsson Comprehensive Cancer Center of the University of California, Los Angeles stated a quote while describing that, “We didn’t know if chemotherapy benefited women in this range. The study showed that if you take the group as a whole, there is no difference in the risk of recurrence when you compare chemotherapy to no chemotherapy”

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Trump’s pardoning of Dinesh D’Souza is to correct an injustice. But, it is reported that the pardon was actually prompted by a desire of the U.S. President for purgation as well as releasing a political notice as intended to aim an American attorney and special counsel, Robert Mueller.

Dinesh D’Souza is a controversial conservative critic, who pleaded guilty to a felony infringement of government’s campaign finance regulations in 2014, while there is definitely no judicial issue with the recent announcement of pardoning him by the U.S. President Donald Trump.

pardon of D’Souza will enable the President to crook the muscles of his executive branch, comforting himself in handling the other matters out of his control, especially the current special counsel investigation and his evident displeasure with Jeff Sessions, Attorney General, which are the major issues rankling president’s spirit.

President Donald Trump said in a statement that, “I’ve always felt he was very unfairly treated. What should have been a quick minor fine, like everybody else with the election stuff….what they did to him was horrible. Plenty of other politicians have said a lot worse. He shouldn’t have been put in jail.”

Barbara Underwood, New York Attorney General disclosed a statement that pleads with state lawmakers, on Thursday wrote that, “President Trump’s latest pardon makes crystal clear his willingness to use his pardon power to thwart the cause of justice, rather than advance it. First it was Sheriff Joe Arpaio. Then it was Scooter Libby. Now it’s Dinesh D’Souza. We can’t afford to wait to see who will be next.”

 

 

 

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NBA combines augmented reality with 360 Portals in the new NBA AR app by the National Basketball Association inviting fans to experience indelible and behind-the-scenes moments of the NBA 2018 Finals and Playoffs.

The new NBA AR app has now been made freely available for Android devices, which was initially launched just for iPhones by October 2017. The app will also offer special content for on-demand NBA Finals, which will be obtained and availed all through the series, in order to feature a variety of experiences of NBA Playoffs such as player introductions, post game celebrations and team huddles.

A virtual door will also be superimposed in the 360 Portals with the help of Google ARCore and Apple ARKit technologies, through fans can immerse themselves in all the NBA action. In addition, the 360-degree videos of major events that are widely followed including NBA games are available already on different online platforms.

Since, the new addition of portal adventure by NBA makes the app more worthy to experience. It makes people feel more exciting and immersive about the features within 360 Portals. The new NBA AR app can be downloaded from the App store or Google Play.

Executive Vice President of Digital Media at the National Basketball Association, Melissa Rosenthal Brenner stated that, “360 Portals will bring NBA fans behind the scenes and onto the court, providing a new way to experience the game through augmented reality. We hope fans around the world check out the NBA AR app throughout the Finals for a unique perspective on our biggest event of the year.”

 

 

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Newcastle scientists designed first 3D printed human cornea. The novel discovery has been made after mixing stem cells obtained from cornea of a healthy donor with a seaweed-derived gel, known as alginate and collagen, which helps form a bio ink solution for printing.

With the help of relatively inexpensive 3D bio-printer, the bio-ink derived from collagen was expelled on the concentric circles in order to create the structure like human cornea, which needed no more than 10 minutes to print.

The first 3D printed corneas have been designed by researchers from the Newcastle University in United Kingdom that yet need to undergo further testing. This proof of concept study is released today in the journal – Experimental Eye Research.

New discovery could break the deficiency of eye donors’ availability and ultimately succor million number of blind people get their sight back, as the corneas are the outermost, transparent layer of the human eye that plays a crucial part in eyesight.

Scientists involved in designing the cornea have used the data gained from scanning an eye of a patient, with the help of which they could print the cornea rapidly, matching the shape and size of the original one. However, its dimensions were taken from the original cornea at the beginning.

Leading researcher of the study and tissue engineering professor, Che Connon from the Newcastle University said in a statement that, “Many teams across the world have been chasing the ideal bio-ink to make this process feasible. Our unique gel — a combination of alginate and collagen — keeps the stem cells alive whilst producing a material which is stiff enough to hold its shape but soft enough to be squeezed out the nozzle of a 3D printer

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Great Barrier Reef suffers 5th near-death experience in 30,000 years, which showed it an each sort of rises in the sea level, increasing sediment and changing temperature.

More acidic and warmer ocean under severe stress, the Great Barrier Reef in Australia has just got a sixth life since the past 30,000 years after experiencing a near-extinction event for fifth time in the period, which indicates that the reef is very much resilient than ever thought, as reported by associated researchers on Monday.

The research team determined by analyzing the fossil data obtained from the cores drilled in the 16 sites of the ocean floor that Great Barrier Reef was capable of migrating from 20 centimeters (i.e. 7.9 inches) to 5 meters a year.

During the investigation, the team found that the reef has had ever suffered through two ubiquitous occurrences because of the exposure with air nearly 22,000 and 30,000 years back, so that the reef shifted towards the sea in order to survive. later, two more near-extinction conditioned were faced by the reef because of rapidly rising sea level as about 13,000 and 17,000 years ago, after which the reef shifted backward to the land.

Co-authored of the paper published in the Nature Geoscience journal, Jody Webster from the University of Sydney said in a statement that, “I have grave concerns about the ability of the reef in its current form to survive the pace of change caused by the many current stresses and those projected into the near future.”

 

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Is Essential phone 2 expelled from launching? according to the Bloomberg’s recent reports, the Android co-creator, helming the smartphone company – Andy Rubin has stopped developing the yet to come Essential Phone 2 model, along with shopping the company itself by dealing with major key buyers. Now the engineers working on the phone are shifted on the smart home applications considering the next year release.

In August, last year, Essential released the first smartphone ever developed by the company naming as Essential PH-1, which received a notable count of fanfare and hype. The phone was made built up from premium materials such as ceramic and titanium, due to which the flagship model was considered as the perfect Android phone according to the imagination made by Rubin.

But later review about the phone expressed a conclusion that the phone knock downs a shorter potential within it, carrying a camera which was among less than the category of exceptionally good, along with a screen that could be designed much better. However, the customers also complained earlier regarding the stagnant and sluggish quality of the phone’s touchscreen.

A spokesperson from Essential said in a statement that, “We always have multiple products in development at the same time and we embrace canceling some in favor of the ones we think will be bigger hits. We are putting all of our efforts towards our future, game-changing products, which include mobile and home products.”

To establish a brand new smart device company, and more importantly with no huge carrier support of the United States, is extremely difficult. And now, it may soon to see another smartphone competitor departing from the market.

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Mothers binging alcohol can harm their offspring’s mental health, says a recent study released by the journal Frontiers in Psychiatry. A team of researcher from Italy has just found more depressive impacts of binge drinking on offspring, during an experiment conducted on rat model.

While, science has previously suggesting that the habitual drinking is as harmful as it can introduce oneself with some sort of anxiety conditions in the pregnant women as well as their offspring, the latest research has claimed that binge or intermittent habit of drinking alcohol can lead to arrive extremely depressive influence.

Researchers from the University of Palermo in Palermo, Italy examined the repercussion occurred because of maternal drinking in any form either intermittently or continuously on the corresponding offspring, by attempting practical research on the rat model. During the research, water mixed with alcohol was given to the pregnant rat who was also a lactating mother.

Leading author of the study, Dr. Carla Cannizzaro from the University of Palermo described the research that, “Chronic and binge alcohol use can disrupt the homeostasis of brain regions relevant for reward. Such use may lead to addiction, craving, loss of control over the use of the substance and severe withdrawal symptoms when the substance is interrupted.”

Dr. Cannizzaro further explained as, “Alcohol or other drugs of abuse — in chronic or in excessive amounts — can imprint genetic encoding and promote heritable modifications. Chronic and binge alcohol use can disrupt the homeostasis of brain regions relevant for reward.”

 

 

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Living human cells just shown weird DNA structure that resembles a four-stranded knot and not like the graceful double helix, about which we have been learning since school.

One of the scientific triumph stories, DNA structure discovery is the combined efforts by four scientists who associated together to decode one of the most mysterious job of nature to produce genes. But now after decades of the discovery humans are still researching for the firm conclusions and consider the subject as intensely complex part of the biological machinery.

Recently discovered unique structure may shed a new light on the long standing research of DNA theories. However, the new findings have been published in the Nature Chemistry journal on Monday by the research team of Kinghorn Centre for Clinical Genomics, the Garvan Institute of Medical Research in Sydney. The new DNA structure appears like a four stranded knot, which the scientists are calling as ‘i-motif’.

Director of the Garvan Institute’s Centre for Targeted Therapy and study’s co-author, Daniel Christ says that, “This raised a scientific debate concerning the biological relevance of this motif. We are providing first direct evidence that i-motif structure exist in cells under physiological conditions. We consider it likely that the formation of i-motifs in promoter regions fine-tunes the expression of corresponding genes.”

Medical chemist, Laurence Hurley from the University of Arizona says, “They essentially form a scaffold, where each C-C bond is 90 degrees to its corresponding C-C pair. It’s clear that these structures [i-motifs] are implicated in gene expression. This paper provides the icing on the cake.”

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NASA aims ‘lunar space station’ materializing by 2019, in order to explore more data about the moon as well as the environment around the space. The space station may provide in the form of gateway for the astronauts voyaging to the space and come back to the Earth, so the agency is calling the construction to be built as ‘Lunar Orbital Platform-Gateway’.

The first speculation by NASA for the new space construction is said to be dedicated to the power elements and propulsion by beginning of the next year, after which the residential components will be lined up, according to the statement by the Associate Administrator of Human Exploration and Operation at NASA, William H. Gerstenmaier.

Gerstenmaier further reported that the new lunar space station is supposed to begin its process of orbiting around the moon along with carrying a crew consisting four astronauts for 30 days of the mission.

“The platform should be orbiting the moon in 2025, a 41-year NASA veteran who oversees human exploration and operations. It will carry a four-astronaut crew on 30-day missions,” in a statement said Gerstenmaier. “We want to understand orbital mechanics around the moon a little better, far from the Earth’s deep gravity well. Doing things in this region, where gravity isn’t such a big driver … is a different way of operating.”

“It can adapt to commercial partners. It’s not a rigid program of one mission following another, an allusion to the Apollo program, which famously required an aggressive schedule of flights that built off each other. As long as we view the moon as a stepping stone and not an end goal, I think we’re OK,” he added.

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Fatty stomach magnifies major heart attack risk by two times more than the people who don’t have fat around their belly. The problem has also been found among the people who are not obese, but have a fatty stomach, and less likely to catch the obese people with lesser weight around their stomach and belly.

Excess fat is long been considered to be linked with heart health, as body fat has substantial impact on the heart. Nearly 1700 people from Olmsted County, Minnesota who were ageing around 45 years old or above were enrolled to the research between the time scale 1997 and 2000.

“People with a normal weight but a fat belly have more chance of heart problems than people without a fat belly, even if they are obese according to BM,” said Dr Medina-Inojosa, study’s leading author, from the Preventive Cardiology department at the Mayo Clinic in Rochester, Minnesota. “This body shape indicates a sedentary lifestyle, low muscle mass, and eating too many refined carbohydrates.”

With the help of medical records obtained by the Rochester Epidemiology Project, the study followed the participants for the risk of developing major adverse cardiovascular events like stroke, cardiovascular death and heart attack.

“The belly is usually the first place we deposit fat, so people classified as overweight BMI but without a fat belly probably have more muscle which is good for health,” Dr Medina-Inojosa continued. “Our study provides evidence that doctors should also measure central obesity to get a better picture of whether a patient is at risk.”

 

 

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Heart-healthy practices avert atrial fibrillation risk, which is one of the most critical disorders that can lead to the irregular heart rhythms, according to the recently discovered findings.

A comprehensive research conducted in the United States involved a middle aged group of men and women for nearly 25 years. the research later came to the conclusion that the people who strictly follow a set of seven practices that recommended as healthy for keeping heart well and fit, have a significantly decreased risk of developing atrial fibrillation by more than 60 per cent, as compared to those people who follow just few or none of the practices listed for the healthy heart.

The review disclosed by the Journal of the American Heart Association claims that the most generally found heart rhythm disorder i.e. atrial fibrillation has affected around 2 million people in the United States.

Dr. Parveen Garg, a cardiologist from the University of Southern California in Los Angeles said in a statement that, “A heart rhythm disorder is something where your heartbeat is not beating regularly, so whenever your heartbeat is not beating regularly, it’s called an arrhythmia. That’s a big deal, because this arrhythmia, if untreated, can lead to stroke.”

Yet more study is required, while the comprehensive and lengthy research needs to show that the modifications in the risk factor that may lead to cut the atrial fibrillation risk are extremely expensive.

“This very timely study shows how risk factor modification, by attacking multiple risk factors simultaneously can have a significant impact on the development of atrial fibrillation,” said a cardiologist at the University of Illinois in Chicago, Dr. Dawood Darbar.

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Brain science institute receives $100 million by graduate alumnus – Robert J. Carney and wife, Nancy D. Carney, as one of the biggest single donation the Brown University has received ever in the history. Now the Brown Institute for Brain Science will be identified as the Robert J. and Nancy D. Carney Institute of Brain Science admiring the donation, as reported during the press release held by the university.

The donation has been basically gifted with intension to accelerate the development in the neuroscience study in Rhode Island along with the new promises to enhance the effectiveness of new cures and treatments over the deadly conditions such as amyotrophic lateral sclerosis and Alzheimer’s disease.

Neuroscience professor and president-elect at the Society for Neuroscience, Diane Lipscombe said, “Our focus is at the early stage, what is going wrong and can we find ways to stop the degeneration”, while Christina Paxson, Brown president said, “This is a signal moment when scientists around the world are poised to solve some of the most important puzzles of the human brain.”

Diane Lipscombe, director of the institute hopes the donation can help decipher the neuron deaths in case of neurodegenerative disorders as well as the comprehension of brain mechanisms, which may eventually help in treating the neurodegenerative disorders.

Christopher Moore, Associate Director of the Institute said in a statement that, “The gift is not so we can take a moonshot at curing some single disease. What this gift will do is it’s going to underwrite the great discoveries that will cure those diseases. It’s going to create the environment in which they can be addressed at the deepest level.”

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Accentuating plants’ robust DNA damage repair system that flawlessly protects them from UV radiation, which is simultaneously essential as well as dangerous for human beings, since numerous people suffer with damages in DNA and skin cancer due to the radiations.

What about plants? Are they also in danger? No, fortunately they are safe, because they have a special system in their DNA that constantly protects them from UV radiation. It is the system within their DNA having role in repairing the damages happening with the DNA, which is somewhat similar to the damage repair system in the humans and animals.

Findings have been disclosed by the journal Nature Communications of the study performed by a team of researchers, one of whom is Ogun Adebali, a postdoctoral scientist at the Aziz Sancar laboratory of the North Carolina University.

For the study, the team worked on the UV-exposed plant – Arabidopsis thaliana or thale cress DNA. “These findings advance our understanding of DNA repair mechanisms common among all organisms and may also have practical applications”, Ogun Adebali said while explaining the research.

Postdoctoral researcher from the Sancar lab, Onur Oztas said in a statement that, “This implies that excision repair is needed to fix DNA damage from other, unknown factors besides UV. We’d like to identify and characterize those unknown factors and find out how excision repair fixes the types of damage they cause. Here we found that the jump in efficiency for transcription-coupled repair is even more pronounced in plants than it is in animals or bacteria.”

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